Genetic Determinants of Lung Cancer Prognosis in Never Smokers: A Pooled Analysis in the International Lung Cancer Consortium.

Yonathan BrhanePing Yang David Chistopher Christiani Geoffrey LiuJohn R McLaughlinPaul J BrennanSanjay SheteJohn K Field Adonina Tardón Takashi KohnoKouya ShiraishiKeitaro Matsuo Yohan Bosse Christopher Ian Amos Rayjean J Hung

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2020)

We identified one locus near LMO7DN at genome-wide level and several potential prognostic genes with cis-effect on mRNA expression. Further functional genomics work is required to understand their role in tumor progression.

Keyphrases

genome wide
dna methylation
copy number
poor prognosis
smoking cessation
single cell
gene expression
human health
long non coding rna
climate change
genome wide analysis