Effect of human endogenous retrovirus-K env gene knockout on proliferation of ovarian cancer cells.

Eun-Ji KoEun Taeg KimHeungyeol KimChul Min LeeSuk Bong KohWan Kyu EoHongbae KimYoung Lim OhMee Sun OckKi Hyung KimHee Jae Cha

Published in: Genes & genomics (2022)

The results of this study showed that HERV-K env gene KO affects cell proliferation, invasion, and migration of ovarian cells through RB and Cyclin B1 proteins, but the specific regulation pattern can differ by cell line.

Keyphrases

cell proliferation
cell cycle arrest
induced apoptosis
cell cycle
copy number
genome wide
endothelial cells
signaling pathway
pi k akt
genome wide identification
cell death
dna methylation
endoplasmic reticulum stress
pluripotent stem cells
genome wide analysis