Biological responses following one-stage full-mouth scaling and root planing with and without azithromycin: Multicenter randomized trial.

Akihiro YashimaToshiya MorozumiHiromasa YoshieTakahiro HokariYuichi IzumiTatsuya AkizukiKoji MizutaniHideyuki TakamatsuMasato MinabeSatomi MiyauchiToshiaki YoshinoMaki TanakaYoshie TanakaKazuhiro Gomi

Published in: Journal of periodontal research (2019)

FM-SRP resulted in similar improvements in clinical parameters with and without the use of AZM. Inflammatory mediators showed no difference between the two groups after FM-SRP treatment. The use of AZM was effective in preventing the elevation of body temperature after FM-SRP.

Keyphrases

oxidative stress
cross sectional
combination therapy
replacement therapy