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DTYMK Expression Predicts Prognosis and Chemotherapeutic Response and Correlates with Immune Infiltration in Hepatocellular Carcinoma.

Yiwen GuoWeixin LuoShanzhou HuangWenting ZhaoHuadi ChenYihao MaMaodong YeYu NieYixi ZhangChangjun HuangQi ZhouXiaoshun HeMaogen Chen
Published in: Journal of hepatocellular carcinoma (2021)
We found that DTYMK has potential as a new prognostic and chemotherapeutic response biomarker for HCC patients and correlates with the immune microenvironment in HCC. However, there are some deficiencies in our study. First, this is a retrospective study that may lead to selection bias. Second, the protein expression of DTYMK was investigated via immunohistochemical analysis. Finally, we did not explore the exact underlying molecular mechanisms of DTYMK in tumorigenesis in this study, which is needed to be clarified in future research.
Keyphrases
  • stem cells
  • ejection fraction
  • end stage renal disease
  • poor prognosis
  • newly diagnosed
  • high resolution
  • binding protein