Autoinflammation in Syndromic Hidradenitis Suppurativa: The Role of AIM2.

Chiara Moltrasio Rachele Cagliani Manuela Sironi Mario Salvatore ClericiChiara PontremoliCarlo Alberto Maronese Paola Maura Tricarico Sergio Crovella Angelo Valerio Marzano

Published in: Vaccines (2023)

Our data suggest that this variant might play a role in susceptibility to develop syndromic forms of HS but not to progress to sporadic HS and PG. Furthermore, epigenetic and/or somatic variations could affect AIM2 expression leading to different, context-dependent responses.

Keyphrases

hidradenitis suppurativa
intellectual disability
poor prognosis
dna methylation
electronic health record
gene expression
late onset
autism spectrum disorder
copy number
big data
early onset
genome wide