Single-dose pharmacokinetics and lung function of nebulized niclosamide ethanolamine in sheep.
Anne WeissRobert J BischofCornelia B LandersdorferTri-Hung NguyenAndrew DaviesJibriil IbrahimPaul WynnePhillip WrightGünter DitzingerA Bruce MontgomeryEls MeeusenMichelle P McIntoshMorten Otto Alexander SommerPublished in: Pharmaceutical research (2023)
Single local pulmonary administration of niclosamide via nebulization was well tolerated in sheep and resulted in substantially higher peak ELF concentration compared to the human equivalent oral 2 g dose.