Microcirculatory consequences of limb ischemia/reperfusion in ovariectomized rats treated with zoledronic acid.

Levente PócsÁgnes JanovszkyImre OcsovszkiJózsef KaszakiJózsef PiffkóAndrea Szabó

Published in: Journal of orthopaedic surgery and research (2019)

The present data do not show substantial postischemic periosteal microcirculatory complications after chronic ZOL treatment either in sham-operated or OVX rats. The unaltered extent of limb IR-induced local periosteal microcirculatory reactions in the presence of reduced CD11b adhesion molecule expression on circulating PMNs, however, may be attributable to local endothelial injury/activation caused by ZOL.

Keyphrases

poor prognosis
high glucose
endothelial cells
drug induced
diabetic rats
electronic health record
big data
oxidative stress
biofilm formation
escherichia coli
machine learning
bone loss
candida albicans
cell migration