Depressive Symptoms and Plasma Markers of Alzheimer's Disease and Neurodegeneration: A Coordinated Meta-Analysis of 8 Cohort Studies.

Emma L TwaitMaria KamariotiInge M W VerberkCharlotte E TeunissenAstrid C J NooyensW M Monique VerschurenPieter Jelle VisserMartijn HuismanAlmar A L KokP Eline SlagboomMarian BeekmanDina VojinovicNico LakenbergM Arfan IkramIsabel K SchuurmansFrank J WoltersJustine E F MoonenLotte GerritsenWiesje M van der FlierMirjam I Geerlingsnull null

Published in: The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry (2024)

Late-life depressive symptoms did not show an association to plasma biomarkers of AD pathology. However, in APOE ε4 allele carriers, a more profound role of neurodegeneration was suggested with depressive symptoms.

Keyphrases

depressive symptoms
social support
cognitive decline
sleep quality
type diabetes
autism spectrum disorder
physical activity