Decreasing mRNA HMGB1 expression in Klebsiella pneumoniae infection treated by Miana ( Coleus scutellarioides (L.) Benth): a cohort experimental study.
Risky AkaputraMochammad HattaMuhammad N MassiIrawati DjaharuddinAgussalim BukhariAminuddin AminuddinArif SantosoRosdiana NatzirBurhanudin BaharMuhammad FachriFarsida FarsidaAgus FathimahFirda M UbaidahEva SridianaRessy DwiyantiAhmad SyukriAde R JunitaAndini FebriantiMuhammad R PrimagunaAzhar AzharPublished in: Annals of medicine and surgery (2012) (2023)
infection inhibited the increase in mRNA HMGB1 expression. Treatment with levofloxacin reduced the level of mRNA HMGB1 expression, and the effect was optimized by the administration of Miana leaf extract as a supplement.