The Effectiveness of Dual-Staining Immunohistochemistry in the Detection of Mantle Cell Lymphoma in the Bone Marrow.

Ifeyinwa Emmanuela ObiorahHao-Wei WangDavid MaEddie MartinWyndham H WilsonRaul Braylan

Published in: American journal of clinical pathology (2022)

Cyclin D1/CD79a and PAX5/CD5 dual IHC staining is an efficient procedure for the detection of MCL in the marrow and is particularly helpful in low-level or focal involvement by MCL. This approach can be particularly useful when marrow aspirates are inadequate or unavailable.

Keyphrases

bone marrow
loop mediated isothermal amplification
real time pcr
label free
randomized controlled trial
mesenchymal stem cells
systematic review
cell cycle
nk cells
flow cytometry
cell proliferation
cell cycle arrest
pi k akt