Pregnancy-specific continuous reference intervals for haematology parameters from an Australian dataset: A step toward dynamic continuous reference intervals.

This is the first study to use an LMS approach to model gestational age-dependent variations in haematological parameters. Proposed haemoglobin reference intervals were lower than those published but reflect our patient population. Serial monitoring of antenatal patients, as is the standard of care, in conjunction with these centile charts, may highlight trends in red cell changes with advancing gestation, allowing early identification of adverse pregnancy outcomes and evolving anaemia.