Parkinson's disease patients have a complex phenotypic and functional Th1 bias: cross-sectional studies of CD4+ Th1/Th2/T17 and Treg in drug-naïve and drug-treated patients.

Natasa KustrimovicCristoforo ComiLuca MagistrelliEmanuela RasiniMassimiliano LegnaroRaffaella BombelliIva AleksicFabio BlandiniBrigida MinafraGiulio RiboldazziAndrea SturchioMarco MauriGiorgio BonoFranca MarinoMarco Cosentino

Published in: Journal of neuroinflammation (2018)

The complex phenotypic and functional profile of CD4+ T cell subsets in PD patients strengthen the evidence that peripheral adaptive immunity is involved in PD, and represents a target for the preclinical and clinical assessment of novel immunomodulating therapeutics.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
cross sectional
peritoneal dialysis
prognostic factors
stem cells
emergency department
small molecule
patient reported outcomes
bone marrow
mesenchymal stem cells