Achyranthes bidentata polypeptide protects dopaminergic neurons from apoptosis in Parkinson's disease models both in vitro and in vivo.

Su PengCaiping WangJinyu MaKetao JiangYuhui JiangXiaosong GuCheng Sun

Published in: British journal of pharmacology (2018)

Taken together, our data show that ABPPk protects dopaminergic neurons from apoptosis, suggesting that ABPPk might be an effective intervention for treating the neuron loss associated with disorders such as PD.

Keyphrases

endoplasmic reticulum stress
cell cycle arrest
oxidative stress
spinal cord
cell death
randomized controlled trial
electronic health record
big data
machine learning
pi k akt
signaling pathway
deep learning