Lung microbial and host genomic signatures as predictors of prognosis in early-stage adenocarcinoma.
Jun-Chieh J TsayFares DarawshyChan WangBenjamin KwokKendrew K WongBenjamin G WuImran SulaimanHua ZhouBradley IsaacsMatthias C KuglerElizabeth SanchezAlexander BainYonghua LiRosemary SchlugerAlena LukovnikovaDestiny CollazoYaa KyerematengRay G PillaiMiao ChangQingsheng LiRami S VanguriAnton Sebastian BeckerWilliam H MooreGeorge D ThurstonTerry GordonAndre L MoreiraChandra M GoparajuDaniel H StermanAristotelis TsirigosHuilin LiLeopoldo N SegalHarvey I PassPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2024)
This study suggests that LUAD recurrence is associated with distinct pathophysiological mechanisms of microbial-host interactions in the unaffected lung rather than those present in the resected tumor.