Age-Dependent Presentation and Clinical Course of 1465 Patients Aged 0 to Less than 18 Years with Ovarian or Testicular Germ Cell Tumors; Data of the MAKEI 96 Protocol Revisited in the Light of Prenatal Germ Cell Biology.
Gabriele CalaminusDominik T SchneiderDietrich von SchweinitzHeribert JürgensNacera InfedStefan SchönbergerThomas A OlsonPeter AlbersChristian VokuhlRaimund SteinLeendert LooijengaJalid SehouliMartin MetzelderAlexander ClaviezMichael DworzakAngelika EggertBirgit FröhlichNicolas U GerberChristian P KratzJörg FaberThomas KlingebielDieter HarmsUlrich GöbelPublished in: Cancers (2020)
The different pathogenesis and histogenesis of gonadal GCT reflects sex- and age-specific patterns that define clinically relevant risk groups. Therefore, gender and age should be considered in further research on the biology and clinical practice of pediatric gonadal GCT.