Persistent depressive symptoms are associated with frontal regional atrophy in patients with Alzheimer's disease.

Lindsey Isla SinclairClive G Ballardnull null

Published in: International journal of geriatric psychiatry (2022)

We have found mixed evidence of increased regional atrophy in depression in AD, mainly in frontal brain regions. We found no evidence to support a vascular basis for depression in AD.

Keyphrases

depressive symptoms
sleep quality
functional connectivity
resting state
social support
working memory
white matter
cognitive decline
multiple sclerosis
brain injury
blood brain barrier