Comprehensive multicomponent characterization and quality assessment of Shuang-Huang-Lian powder injection using ultra-high-performance liquid chromatography-quadrupole time-of-flight-mass spectrometry and ultra-high-performance liquid chromatography-quadrupole-Orbitrap-mass spectrometry.
Jiaxin YinChao LiJie ZhangHui DingLifeng HanWenzhi YangFangyi LiXinbo SongSongtao BieHeshui YuZheng LiPublished in: Rapid communications in mass spectrometry : RCM (2023)
This work comprehensively characterized the material basis of SHLPI, summarized the cracking laws of representative substances, and quantitatively analyzed 10 potential allergenic components. Therefore, this study could provide a basis for the quality control of SHLPI and the clinical rational use of drugs to reduce its adverse reactions.
Keyphrases
- ultra high performance liquid chromatography
- tandem mass spectrometry
- liquid chromatography
- mass spectrometry
- high resolution mass spectrometry
- high performance liquid chromatography
- gas chromatography
- quality control
- simultaneous determination
- high resolution
- solid phase extraction
- drinking water
- cross sectional
- emergency department
- risk assessment
- ms ms
- human health
- drug induced