Suvorexant alters dynamics of the sleep-electroencephalography-power spectrum and depressive-symptom trajectories during inpatient opioid withdrawal.

Matthew J ReidKelly E DunnLiza AbrahamJennifer Danielle EllisCarly HuntCharlene E GamaldoWilliam G CoonChung Jung MunEric C StrainMichael T SmithPatrick H Finan Andrew S Huhn

Published in: Sleep (2024)

Results highlight a complex and nuanced relationship between sleep-EEG power and symptoms of depression and withdrawal. Changes in delta power may represent a mechanism influencing depressive symptoms and withdrawal.

Keyphrases

depressive symptoms
sleep quality
social support
physical activity
pain management
functional connectivity
working memory
stress induced