The Flow brain stimulation headset for the treatment of depression: overview of its safety, efficacy and portable design.
Lucas BorrionePaulo Jeng Chian SuenLaís B RazzaLeonardo Afonso Dos SantosPedro Sudbrack-OliveiraAndre Russowsky BrunoniPublished in: Expert review of medical devices (2020)
Electric field simulations revealed that Flow's tDCS device targets prefrontal cortical areas involved in MDD pathophysiology. In addition, the safety and efficacy profile revealed from prior tDCS studies support its use in depression. Finally, combining tDCS with cognitive-behavioral interventions might further enhance overall efficacy, although this aspect should be investigated in upcoming randomized, placebo-controlled trials.
Keyphrases
- transcranial direct current stimulation
- placebo controlled
- double blind
- working memory
- depressive symptoms
- phase iii
- single cell
- phase ii
- sleep quality
- open label
- functional connectivity
- resting state
- physical activity
- clinical trial
- white matter
- study protocol
- molecular dynamics
- transcranial magnetic stimulation
- randomized controlled trial
- radiation therapy
- mass spectrometry
- high frequency
- brain injury
- bipolar disorder
- cerebral ischemia
- subarachnoid hemorrhage
- single molecule
- high speed