Prenatal dexamethasone treatment for classic 21-hydroxylase deficiency in Europe.
Hanna NowotnyUta NeumannVéronique Tardy-GuidolletSyed Faisal AhmedFederico BaronioTadej BattelinoJérôme BertheratOliver BlankensteinMarco BonomiClaire BouvattierAude Brac de la PerrièreSara BruckerMarco CappaPhilippe ChansonHedi L Claahsen-van der GrintenAnnamaria ColaoMartine CoolsJustin H DaviesHelmut-Günther DörrWiebke K FenskeEzio GhigoRoberta GiordanoClaus H GravholtAngela HuebnerEystein Sverre HusebyeRebecca IgbokweAnders JuulFlorian W KieferJuliane LégerRita MenassaGesine MeyerVassos NeocleousLeonidas A PhylactouJulia RohayemGianni RussoCarla ScaroniPhilippe A TouraineNicole UngerJarmila VojtkováDiego YesteSvetlana LajicNicole ReischPublished in: European journal of endocrinology (2022)
This study reveals a high international variability and discrepancy in the use of Pdex treatment across Europe. It highlights the importance of a European cooperation initiative for a joint international prospective trial to establish evidence-based guidelines on prenatal diagnostics, treatment and follow-up of pregnancies at risk for CAH.