Ubiquitin-specific protease 7 as a potential therapeutic target in dogs with hematopoietic malignancies.
Aleksandra PawlakJoanna BajzertKatarzyna BugielBeatriz Hernández SuárezJustyna KutkowskaAndrzej RapakWojciech HildebrandBożena Obmińska-MrukowiczRaimundo FreireVeronique A J SmitsPublished in: Journal of veterinary internal medicine (2021)
Our results suggest that USP7 could be explored as a potential therapeutic target in dogs with lymphoma. The effectiveness of USP7 inhibition in malignant cells is predicted to be independent of their p53 status.