Macrophage migration inhibitory factor regulates specific innate immune sensor responses in gingival epithelial cells.

Nutthapong KantrongAna M ChangShatha BamashmousAdeline M HajjarRichard John BucalaRichard P Darveau

Published in: Journal of periodontology (2022)

MIF regulates the expression of TLR4, IL-1Rs, and IL-8/CXCL8, components that are all involved in maintaining oral health. Our data demonstrate that MIF is a significant contributor to the maintenance of healthy oral homeostasis.

Keyphrases

innate immune
oral health
poor prognosis
toll like receptor
inflammatory response
immune response
adipose tissue
electronic health record
binding protein