Safety of SABA Monotherapy in Asthma Management: a Systematic Review and Meta-analysis.

Thitiwat Sriprasart Grant W. WatererGabriel GarciaAdalberto Sperb RuninMarco Antonio Loustaunau AndradeAgnieszka Roguska Abhay PhansalkarSourabh FulmaliAmber Martin Lalith Mittal Bhumika Aggarwal Gur Levy

Published in: Advances in therapy (2022)

Meta-analysis of data from RCTs showed that deaths were rare with SABA reliever monotherapy, and rates of SAEs and DAEs were comparable between SABA reliever and ICS treatment groups. When used appropriately within prescribed limits as reliever therapy, SABA does not contribute to excess rates of mortality, SAEs, or DAEs.

Keyphrases

combination therapy
open label
chronic obstructive pulmonary disease
cardiovascular events
electronic health record
lung function
risk factors
randomized controlled trial
big data
clinical trial
mesenchymal stem cells
deep learning
cell therapy
study protocol