Bovine Colostrum Against Chemotherapy-Induced Gastrointestinal Toxicity in Children With Acute Lymphoblastic Leukemia: A Randomized, Double-Blind, Placebo-Controlled Trial.
Mathias RatheSilvia De PietriPeder Skov WehnerThomas Leth FrandsenKathrine GrellKjeld SchmiegelowPer Torp SangildSteffen HusbyKlaus MüllerPublished in: JPEN. Journal of parenteral and enteral nutrition (2019)
The use of prophylactic bovine colostrum showed no effect on fever, infectious morbidity, or inflammatory responses. Nevertheless, these data may suggest protective effects on the oral mucosa during induction therapy in childhood ALL, encouraging additional studies confirming these findings.
Keyphrases
- double blind
- chemotherapy induced
- acute lymphoblastic leukemia
- human milk
- placebo controlled
- clinical trial
- study protocol
- young adults
- allogeneic hematopoietic stem cell transplantation
- electronic health record
- oxidative stress
- phase iii
- big data
- phase ii
- randomized controlled trial
- case control
- childhood cancer
- acute myeloid leukemia
- data analysis
- bone marrow
- smoking cessation