Histoplasmosis-Associated Hemophagocytic Lymphohistiocytosis: A Review of the Literature.
Ra'ed JabrWissam El AtrouniHeather J MaleKassem A HammoudPublished in: The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale (2019)
Histoplasmosis-associated HLH among adults is an uncommon but serious complication with high associated mortality. Early antifungal therapy with a lipid formulation amphotericin B is critical. The initiation of immunosuppressive therapy with regimens like HLH-04 in this disease entity should be individualized.