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Seeding competent TDP-43 persists in human patient and mouse muscle.

Eileen M LynchSara PittmanJil DawChiseko IkenagaSheng ChenDhruva D DhavaleMeredith E JackrelYuna M AyalaPaul KotzbauerCindy V LyAlan PestronkThomas E LloydConrad C Weihl
Published in: bioRxiv : the preprint server for biology (2024)
TDP-43 aggregate seeds persist in mouse and human skeletal muscle independent of large TDP-43 inclusions.
Keyphrases
  • skeletal muscle
  • endothelial cells
  • amyotrophic lateral sclerosis
  • induced pluripotent stem cells
  • type diabetes
  • case report
  • metabolic syndrome
  • adipose tissue