Meredith E Jackrel (Meredith Jackrel)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 23

Top Topics

Amyotrophic Lateral Sclerosis

Top Venues

Nature communications

Biochemical Society transactions

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Macy L Sprunger, Meredith E Jackrel
The role of Matrin-3 in physiology and its dysregulation in disease. Biochemical Society transactions (2024)
Macy L Sprunger, Meredith E Jackrel
The role of Matrin-3 in physiology and its dysregulation in disease. Biochemical Society transactions 52 (3) (2024)
Eileen M Lynch, Sara Pittman, Jil Daw, Chiseko Ikenaga, Sheng Chen, Dhruva D Dhavale, Meredith E Jackrel, Yuna M Ayala, Paul Kotzbauer, Cindy V Ly, Alan Pestronk, Thomas E Lloyd, Conrad C Weihl
Seeding competent TDP-43 persists in human patient and mouse muscle. bioRxiv : the preprint server for biology (2024)
Sheng Chen, Anuradhika Puri, Braxton Bell, Joseph Fritsche, Hector H Palacios, Maurie Balch, Macy L Sprunger, Matthew K Howard, Jeremy J Ryan, Jessica N Haines, Gary J Patti, Albert A Davis, Meredith E Jackrel
HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species. Nature communications 15 (1) (2024)
Eileen M Lynch, Sara Pittman, Jil Daw, Chiseko Ikenaga, Sheng Chen, Dhruva D Dhavale, Meredith E Jackrel, Yuna M Ayala, Paul Kotzbauer, Cindy V Ly, Alan Pestronk, Thomas E Lloyd, Conrad C Weihl
Seeding competent TDP-43 persists in human patient and mouse muscle. bioRxiv : the preprint server for biology (2024)
Sheng Chen, Anuradhika Puri, Braxton Bell, Joseph Fritsche, Hector H Palacios, Maurie Balch, Macy L Sprunger, Matthew K Howard, Jeremy J Ryan, Jessica N Haines, Gary J Patti, Albert A Davis, Meredith E Jackrel
HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species. Nature communications 15 (1) (2024)
Macy L Sprunger, Meredith E Jackrel
The role of Matrin-3 in physiology and its dysregulation in disease. Biochemical Society transactions 52 (3) (2024)
Sheng Chen, Anuradhika Puri, Braxton Bell, Joseph Fritsche, Hector H Palacios, Maurie Balch, Macy L Sprunger, Matthew K Howard, Jeremy J Ryan, Jessica N Haines, Gary J Patti, Albert A Davis, Meredith E Jackrel
HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species. Nature communications 15 (1) (2024)
Sheng Chen, Anuradhika Puri, Braxton Bell, Joseph Fritsche, Hector H Palacios, Maurie Balch, Macy L Sprunger, Matthew K Howard, Jeremy J Ryan, Jessica N Haines, Gary J Patti, Albert A Davis, Meredith E Jackrel
HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species. Nature communications 15 (1) (2024)
Eileen M Lynch, Sara Pittman, Jil Daw, Chiseko Ikenaga, Sheng Chen, Dhruva D Dhavale, Meredith E Jackrel, Yuna M Ayala, Paul Kotzbauer, Cindy V Ly, Alan Pestronk, Thomas E Lloyd, Conrad C Weihl
Seeding competent TDP-43 persists in human patient and mouse muscle. bioRxiv : the preprint server for biology (2024)
Macy L Sprunger, Meredith E Jackrel
The role of Matrin-3 in physiology and its dysregulation in disease. Biochemical Society transactions 52 (3) (2024)
Sheng Chen, Anuradhika Puri, Braxton Bell, Joseph Fritsche, Hector H Palacios, Maurie Balch, Macy L Sprunger, Matthew K Howard, Jeremy J Ryan, Jessica N Haines, Gary J Patti, Albert A Davis, Meredith E Jackrel
HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species. Nature communications 15 (1) (2024)
Eileen M Lynch, Sara Pittman, Jil Daw, Chiseko Ikenaga, Sheng Chen, Dhruva D Dhavale, Meredith E Jackrel, Yuna M Ayala, Paul Kotzbauer, Cindy V Ly, Alan Pestronk, Thomas E Lloyd, Conrad C Weihl
Seeding competent TDP-43 persists in human patient and mouse muscle. bioRxiv : the preprint server for biology (2024)
Sheng Chen, Anuradhika Puri, Braxton Bell, Joseph Fritsche, Hector Palacios, Maurie Balch, Macy Sprunger, Matthew K Howard, Jessica Patterson, Gary J Patti, Albert Davis, Meredith E Jackrel
HtrA1 prevents and reverses α-synuclein aggregation, rendering it non-toxic and seeding incompetent. Research square (2023)
Matthew K Howard, Karlie R Miller, Brian S Sohn, Jeremy J Ryan, Andy Xu, Meredith E Jackrel
Probing the drivers of Staphylococcus aureus biofilm protein amyloidogenesis and disrupting biofilms with engineered protein disaggregases. mBio (2023)
Yeawon Kim, Chuang Li, Chenjian Gu, Yili Fang, Eric Tycksen, Anuradhika Puri, Terri A Pietka, Jothilingam Sivapackiam, Kendrah Kidd, Sun-Ji Park, Bryce G Johnson, Stanislav Kmoch, Jeremy S Duffield, Anthony J Bleyer, Meredith E Jackrel, Fumihiko Urano, Vijay Sharma, Maria Lindahl, Ying Maggie Chen
MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice. Nature communications 14 (1) (2023)
Matthew K Howard, Karlie R Miller, Brian S Sohn, Jeremy J Ryan, Andy Xu, Meredith E Jackrel
Probing the drivers of Staphylococcus aureus biofilm protein amyloidogenesis and disrupting biofilms with engineered protein disaggregases. mBio (2023)
Jeremy J Ryan, Aaron Bao, Braxton Bell, Cendi Ling, Meredith E Jackrel
Drivers of Hsp104 potentiation revealed by scanning mutagenesis of the middle domain. Protein science : a publication of the Protein Society 30 (8) (2021)
Zachary M March, Katelyn Sweeney, Hanna Kim, Xiaohui Yan, Laura M Castellano, Meredith E Jackrel, JiaBei Lin, Edward Chuang, Edward Gomes, Corey W Willicott, Karolina Michalska, Robert P Jedrzejczak, Andrzej Joachimiak, Kim A Caldwell, Guy A Caldwell, Ophir Shalem, James Shorter
Therapeutic genetic variation revealed in diverse Hsp104 homologs. eLife 9 (2020)
Matthew K Howard, Brian S Sohn, Julius von Borcke, Andy Xu, Meredith E Jackrel
Functional analysis of proposed substrate-binding residues of Hsp104. PloS one 15 (3) (2020)
Jeremy J Ryan, Macy L Sprunger, Kayla Holthaus, James Shorter, Meredith E Jackrel
Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcoma. The Journal of biological chemistry 294 (29) (2019)
Kyota Yasuda, Sarah F Clatterbuck-Soper, Meredith E Jackrel, James Shorter, Stavroula Mili
FUS inclusions disrupt RNA localization by sequestering kinesin-1 and inhibiting microtubule detyrosination. The Journal of cell biology 216 (4) (2017)
Stephanie N Gates, Adam L Yokom, JiaBei Lin, Meredith E Jackrel, Alexandrea N Rizo, Nathan M Kendsersky, Courtney E Buell, Elizabeth A Sweeny, Korrie L Mack, Edward Chuang, Mariana P Torrente, Min Su, James Shorter, Daniel R Southworth
Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Science (New York, N.Y.) 357 (6348) (2017)