Predictors of Effectiveness of Anakinra in Systemic Juvenile Idiopathic Arthritis.
Benedetta SaccomannoJessica TibaldiFrancesca MinoiaFrancesca BagnascoAngela PistorioAndressa GuarientoRoberta CaorsiAlessandro ConsolaroMarco GattornoAngelo RavelliPublished in: The Journal of rheumatology (2019)
Our findings help to delineate the clinical profile of patients with sJIA who are more likely to benefit from IL-1 blockade. They also underscore the need for studies aimed at examining the therapeutic role of early IL-1 inhibition and to identify biomarkers predicting response to either IL-1 or IL-6 antagonists.