C-di-AMP accumulation disrupts glutathione metabolism and inhibits virulence program expression in Listeria monocytogenes .
Cheta SilettiMatthew FreemanZepeng TuDavid M StevensonDaniel Amador-NoguezJohn-Demian SauerTuAnh N HuynhPublished in: bioRxiv : the preprint server for biology (2024)
replication in the host. Given the role of GSH as a virulence signal, nutrient, and antioxidant, GSH depletion impairs virulence program expression and likely diminishes host adaptation.