[Surgery for parotid gland cancer-controversial and proven aspects].
Konstantinos MantsopoulosHeinrich IroPublished in: HNO (2022)
In salivary gland oncology there is a trend towards safe (R0) but more conservative surgery. Currently, less-invasive surgical approaches could potentially be applied in a small subgroup with carefully selected caudally located and R0-resected "low-grade tumors" in stages T1-T2 and cN0 in relatively young patients with high compliance and more in the context of structured clinical studies. Elective neck dissection in the case of cN0 status should be carried out if risk factors for occult cervical lymph node metastasis (T3-T4a, "high-grade subtypes," advanced age, lymphangitic carcinomatosis) are present. In cases of small "low-grade parotid carcinomas," narrow resection margins or even microscopic tumor residues on the facial nerve can potentially be adequately compensated with adjuvant radiation therapy. However, due to the lack of solid data, the significance of the actual effect of the radiation in this situation should be viewed with great caution.
Keyphrases
- low grade
- high grade
- lymph node metastasis
- papillary thyroid
- minimally invasive
- squamous cell carcinoma
- coronary artery bypass
- radiation therapy
- palliative care
- surgical site infection
- patients undergoing
- early stage
- radiation induced
- percutaneous coronary intervention
- electronic health record
- randomized controlled trial
- big data
- squamous cell
- coronary artery disease
- young adults
- artificial intelligence
- machine learning
- atrial fibrillation