Individualized Structural Perturbations on Normative Brain Connectome Restrict Deep Brain Stimulation Outcomes in Parkinson's Disease.
Xuyang WangShiyu FuKwangsun YooXiaoyue WangLin GanTing ZouQing GaoHonghao HanZhenzhe YangXiaofei HuHuafu ChenDingyang LiuRong LiPublished in: Movement disorders : official journal of the Movement Disorder Society (2024)
Our findings suggest that individual structural perturbations on the cognitive motor control circuit are critical for modulating DBS outcomes. Interventions toward the circuit have the potential for additional clinical improvements. © 2024 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Keyphrases
- deep brain stimulation
- parkinson disease
- obsessive compulsive disorder
- resting state
- physical activity
- signaling pathway
- white matter
- systematic review
- metabolic syndrome
- randomized controlled trial
- human health
- risk assessment
- multiple sclerosis
- adipose tissue
- blood brain barrier
- glycemic control
- insulin resistance
- meta analyses