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Complex Genomic Rearrangements following Selection in a Glutamine-Limited Medium over Hundreds of Generations.

Pieter SpealmanGrace AvecillaJulia MatthewsIna SureshDavid Gresham
Published in: Microbiology resource announcements (2022)
Large-scale genomic changes, including copy number variations (CNVs), are frequently observed in long-term evolution experiments (LTEEs). We have previously reported the detection of recurrent CNVs in Saccharomyces cerevisiae populations adapting to glutamine-limited conditions over hundreds of generations. Here, we present the whole-genome sequencing (WGS) assemblies of 7 LTEE strains and their ancestor.
Keyphrases
  • copy number
  • saccharomyces cerevisiae
  • mitochondrial dna
  • genome wide
  • dna methylation
  • escherichia coli
  • loop mediated isothermal amplification
  • label free
  • genetic diversity
  • quantum dots