Complex Genomic Rearrangements following Selection in a Glutamine-Limited Medium over Hundreds of Generations.
Pieter SpealmanGrace AvecillaJulia MatthewsIna SureshDavid GreshamPublished in: Microbiology resource announcements (2022)
Large-scale genomic changes, including copy number variations (CNVs), are frequently observed in long-term evolution experiments (LTEEs). We have previously reported the detection of recurrent CNVs in Saccharomyces cerevisiae populations adapting to glutamine-limited conditions over hundreds of generations. Here, we present the whole-genome sequencing (WGS) assemblies of 7 LTEE strains and their ancestor.