Glial-neuronal signaling mechanisms underlying the neuroinflammatory effects of manganese.

Katriana A PopichakMaryam F AfzaliKelly S KirkleyRonald B Tjalkens

Published in: Journal of neuroinflammation (2018)

This suggests that astrocytes are a critical mediator of Mn neurotoxicity through enhanced expression of inflammatory cytokines and chemokines, including those most associated with a reactive phenotype such as CCL2 but not C3.

Keyphrases

poor prognosis
neuropathic pain
liver fibrosis
liver injury
binding protein
room temperature
long non coding rna
transition metal
spinal cord injury
metal organic framework
subarachnoid hemorrhage