Development of a standardized histopathology scoring system for intervertebral disc degeneration in rat models: An initiative of the ORS spine section.
Alon LaiJennifer GansauRobert L MauckJames CrowleyCarla CunhaStefan DudliJulie B EngilesMarion FusellierRaquel M GoncalvesDaisuke NakashimaJeffrey OkewunmiMatthew Henry PelletierSteven M PresciuttiJordy ScholYoshiki TakeokaSidong YangTakashi YurubeYejia ZhangJames C IatridisPublished in: JOR spine (2021)
The proposed histological preparation protocol and grading system provide a platform for more precise comparisons and more robust evaluation of rat IVD degeneration models and interventions across laboratories.