Real-world Effectiveness and Tolerability of Interferon-free Direct-acting Antiviral for 15,849 Patients with Chronic Hepatitis C: A Multinational Cohort Study.
Fanpu JiSally TranEiichi OgawaChung-Feng HuangTakanori SuzukiYu Jun WongHidenori ToyodaDae Won JunLiu LiHaruki UojimaAkito NozakiMakoto ChumaCheng-Hao TsengYao-Chun HsuMasatoshi IshigamiTakashi HondaMasanori AtsukawaHiroaki HagaMasaru EnomotoHuy TrinhCarmen Monica PredaPhillip VutienCharles LandisDong Hyun LeeTsunamasa WatanabeHirokazu TakahashiHiroshi AbeAkira AsaiYuichiro EguchiJie LiXiaozhong WangJia LiJunping LiuJing LiangCarla Pui-Mei LamRui HuangQing YeHongying PanJiajie ZhangDachuan CaiQi WangDaniel Q HuangGrace WongVincent Wai-Sun WongJunyi LiSon DoNorihiro FurusyoMakoto NakamutaHideyuki NomuraEiji KajiwaraEileen L YoonSang Bong AhnKoichi AzumaKazufumi DohmenJihyun AnDo Seon SongHyun Chin ChoAkira KawanoToshimasa KoyanagiAritsune OohoTakeaki SatohKazuhiro TakahashiMing-Lun YehPei-Chien TsaiSatoshi YasudaYunyu ZhaoYishan LiuTomomi OkuboNorio ItokawaMi Jung JunToru IshikawaKoichi TakaguchiTomonori SenohMingyuan ZhangChangqing ZhaoRaluca Ioana AlecuWei Xuan TayPooja DevanJoanne Kimiko LiuRitsuzo KozukaElena Vargas-AccarinoAi-Thien DoMayumi MaedaWan-Long ChuangJee-Fu HuangChia-Yen DaiRamsey CheungMaria ButiJunqi NiuWen XieHong RenSeng Gee LimChao WuMan-Fung YuenJia ShangQiang ZhuYoshiyuki UenoYasuhito TanakaJun HayashiMing-Lung YuMindie H NguyenPublished in: Journal of clinical and translational hepatology (2024)
In this diverse multinational real-world cohort of patients with various GTs, the overall cure rate was 96.9%, despite large numbers of patients with cirrhosis, HCC, TE, and GT3/6. SVR12 for GT3/6 with cirrhosis and TE was lower but still excellent (>91%).