Study protocol for a multicentre implementation trial of monotherapy anticoagulation to expedite home treatment of patients diagnosed with venous thromboembolism in the emergency department.
Jeffrey A KlineDavid AdlerNaomi AlanisJoseph BledsoeDaniel CourtneyJames D'EtienneDeborah B DiercksJohn GarrettAlan E JonesDavid MacKenzieTroy MadsenAndrew MatuskowitzBryn MummaKristen NordenholzJustine PagenhardtMichael RunyonWilliam StubblefieldChristopher WilloughbyPublished in: BMJ open (2020)
All sites had Institutional Review Board approval. We anticipate completion of enrolment in June 2020; study data will be available after peer-reviewed publication. MATH-VTE will provide information from a large multicentre sample of US patients about the efficacy and safety of home treatment of VTE with monotherapy anticoagulation.
Keyphrases
- venous thromboembolism
- direct oral anticoagulants
- emergency department
- study protocol
- healthcare
- clinical trial
- combination therapy
- end stage renal disease
- open label
- newly diagnosed
- primary care
- chronic kidney disease
- peritoneal dialysis
- randomized controlled trial
- atrial fibrillation
- prognostic factors
- double blind
- phase iii
- patient reported outcomes
- health insurance
- electronic health record
- machine learning
- big data
- adverse drug