Effects of tocilizumab on neutrophil function and kinetics.

Laurence S C LokNeda FarahiJatinder K JussChrystalla LoutsiosChandra K SolankiA Michael PetersFrancis DonaldsonBenjamin Porter-BrownEdwin R Chilvers

Published in: European journal of clinical investigation (2017)

We have demonstrated for the first time in humans that IL-6R blockade affects neutrophil trafficking to the bone marrow without influencing neutrophil functional capacity.

Keyphrases

bone marrow
mesenchymal stem cells
juvenile idiopathic arthritis
rheumatoid arthritis patients
disease activity