The Relationship Between Antibiotic Agent and Mortality in Patients With Febrile Neutropenia due to Staphylococcal Bloodstream Infection: A Multicenter Cohort Study.
Muneerah M AleissaIsabel H Gonzalez-BoccoSara Zekery-SaadDavid W KubiakEric M ZhangJessie SignorelliSarah P HammondAmir M MoharebMarlise R LuskinJennifer Manne-GoehlerFrancisco M MartyPublished in: Open forum infectious diseases (2022)
Use of combination beta-lactam therapy in patients with MSSA BSI and febrile neutropenia is associated with a higher mortality compared with treatment with broad-spectrum beta-lactam after adjusting for potential confounders. Patients in this study who transitioned to narrow-spectrum beta-lactam antibiotics did not have worse clinical outcomes compared with those who continued broad-spectrum beta-lactam therapy.
Keyphrases
- gram negative
- chemotherapy induced
- end stage renal disease
- cardiovascular events
- newly diagnosed
- chronic kidney disease
- ejection fraction
- multidrug resistant
- urinary tract infection
- clinical trial
- prognostic factors
- type diabetes
- peritoneal dialysis
- stem cells
- cross sectional
- double blind
- klebsiella pneumoniae
- cell therapy
- smoking cessation