Leptin/osteopontin axis contributes to enhanced T helper 17 type responses in allergic rhinitis.

Wen Long LiuQingxiang ZengLifeng ZhouYan LiYanqiu ChenRenZhong Luo

Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2018)

Our data provide evidence that upregulation of leptin and OPN promotes Th17 responses in AR, and this process may be achieved through NF-κB, MAPK, and JNK pathway and β3 integrin.

Keyphrases

signaling pathway
allergic rhinitis
pi k akt
induced apoptosis
oxidative stress
electronic health record
regulatory t cells
cell proliferation
cell death
poor prognosis
machine learning
nuclear factor
long non coding rna
inflammatory response
deep learning