Status of inflammation in relation to health related quality of life in hepatocellular carcinoma patients.

Leung Li Stephen Lam Chan Frankie K F Mo Edwin Pun Hui Jane Koh Allen K C Chan Nelson Leung-Sang Tang Cheuk M Chu Joyce HuiKit F LeeSimon Chun Ho Yu Winnie Yeo

Published in: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation (2019)

In HCC patients, inflammatory status correlates with HRQoL at presentation. In particular, relatively stronger correlations with CRP-based markers have been observed in HRQoL scales that assess constitutional symptoms (QLQ-C30 'physical functioning', 'role functioning', 'fatigue', 'appetite loss' and QLQ-HCC18 'fatigue' and 'nutrition') and tumor burden (QLQ-C30 'pain' and QLQ-HCC18 'abdominal swelling' and 'body image'). Future studies are warranted to evaluate whether intervention that reduces inflammation could improve HRQoL in HCC patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
randomized controlled trial
physical activity
mental health
chronic pain
spinal cord injury
risk factors
neuropathic pain
body weight
postoperative pain