Leveraging human genetic data to investigate the cardiometabolic effects of glucose-dependent insulinotropic polypeptide signalling.

Ville Karhunen Iyas Daghlas Verena Zuber Marijana Vujkovic Anette K Olsen Lotte Bjerre Knudsen William G Haynes Joanna M M Howson Dipender Gill

Published in: Diabetologia (2021)

All data used in this study are publicly available. The scripts for the analysis are available at: https://github.com/vkarhune/GeneticallyProxiedGIP .

Keyphrases

electronic health record
endothelial cells
big data
genome wide
data analysis
blood glucose
blood pressure
machine learning
pluripotent stem cells
dna methylation
copy number
adipose tissue
insulin resistance