Patient distrust in pharmaceutical companies: an explanation for women under-representation in respiratory clinical trials?
Laurie PahusCarey Meredith SuehsLaurence HalimiArnaud BourdinPascal ChanezDany JaffuelJulie MarcianoAnne-Sophie GamezIsabelle VachierNicolas MolinariPublished in: BMC medical ethics (2020)
Distrust in pharmaceutical companies is associated with a specific patient profile and with refusal to participate in certain subcategories of trials. This potential recruitment bias may explain the under-representation of certain categories of patients such as women in pre-marketing drug trials.
Keyphrases
- clinical trial
- polycystic ovary syndrome
- end stage renal disease
- case report
- ejection fraction
- newly diagnosed
- chronic kidney disease
- randomized controlled trial
- prognostic factors
- type diabetes
- emergency department
- metabolic syndrome
- cervical cancer screening
- pregnant women
- risk assessment
- breast cancer risk
- climate change
- human health
- patient reported outcomes
- drug induced
- patient reported
- respiratory tract
- phase iii