The HUNT lung-SNP model: genetic variants plus clinical variables improve lung cancer risk assessment over clinical models.
Olav Toai Duc NguyenIoannis FotopoulosTherese Haugdahl NøstMaria MarkakiVincenzo LaganiIoannis TsamardinosOluf Dimitri RøePublished in: Journal of cancer research and clinical oncology (2024)
The HUNT Lung-SNP model could have a clinical impact on LC screening and has the potential to replace the HUNT LCM as well as the NLST, NELSON and 2021 USPSTF criteria in a screening setting. However, the model should be further validated in other populations and evaluated in a prospective trial setting.