LncRNA WDFY3-AS2 promotes cisplatin resistance and the cancer stem cell in ovarian cancer by regulating hsa-miR-139-5p/SDC4 axis.

Yue WuTing WangLin XiaMei Zhang

Published in: Cancer cell international (2021)

Together, WDFY3-AS2 may lead to change of cisplatin resistance by the expression of miR-139-5p/SDC4 in the OC A2870-DDP cells both in vitro and in vivo. Our finding may provide a drug target for the drug resistance of OC.

Keyphrases

cancer stem cells
induced apoptosis
poor prognosis
cell cycle arrest
long non coding rna
emergency department
binding protein