The exon junction complex component EIF4A3 is essential for mouse and human cortical progenitor mitosis and neurogenesis.

Bianca M LupanRachel A SoleckiCamila Manso MussoFernando C AlsinaDebra L Silver

Published in: bioRxiv : the preprint server for biology (2023)

This study shows that EIF4A3 mediates neurogenesis by controlling mitosis duration in both mouse and human neural progenitors, implicating new mechanisms underlying neurodevelopmental disorders.

Keyphrases

endothelial cells
induced pluripotent stem cells
pluripotent stem cells
cerebral ischemia
brain injury