Possible Involvement of DNA Methylation in TSC1 Gene Expression in Neuroprotection Induced by Hypoxic Preconditioning.

Ruifang QiYabin XieXiaolu ZhangShuyuan JiangXiaolei LiuWei XieXiaoe JiaRengui BadeYou LiuKerui GongWenjie YangGuanghui GuoKai SunChunyang Zhang Ruijuan Han Guo Shao

Published in: Oxidative medicine and cellular longevity (2022)

TSC1 expression induced by HPC may relate to the downregulation of its DNA methylation level with the increase of autophagy and the decrease of energy demand.

Keyphrases

dna methylation
gene expression
genome wide
signaling pathway
cerebral ischemia
poor prognosis
cell death
endoplasmic reticulum stress
cell proliferation
oxidative stress
ischemia reperfusion injury
brain injury
copy number
binding protein
subarachnoid hemorrhage
long non coding rna