Role of Silver Nitrate Spray for Skin Wound Care in Patients with Toxic Epidermal Necrolysis: Our Experience in 4 Patients.
José Dario MartínezJesus Alberto CardenasManuel SoriaLuis Manuel SaenzKattya EstradaSergio Maximo DelgadoMarius-Anton IonescuCamelia BusilaAlin Laurențiu TatuPublished in: Life (Basel, Switzerland) (2023)
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are examples of severe cutaneous adverse reactions to drugs (SCARs) with several international recommendations for global medical management, ranging from pharmacological systemic therapy to skin wound care. There is no defined best management of the skin wounds in SJS/TEN. The care of wounds is essential to initiate re-epithelialization. Our objective is to improve the cicatrization process, avoiding scarring due to deepening of the wounds, as well as prevent infections, achieve pain control, and avoid loss of serum proteins, fluids, and electrolytes. In this retrospective case series, we highlight the value of systemic therapy and the use of silver nitrate for wound management in four patients with TEN.
Keyphrases
- wound healing
- healthcare
- palliative care
- pain management
- quality improvement
- gold nanoparticles
- nitric oxide
- ejection fraction
- chronic pain
- end stage renal disease
- soft tissue
- newly diagnosed
- drinking water
- cross sectional
- drug induced
- early onset
- spinal cord injury
- emergency department
- surgical site infection
- affordable care act
- silver nanoparticles
- clinical practice
- spinal cord