Efficient and rapid conversion of human astrocytes and ALS mouse model spinal cord astrocytes into motor neuron-like cells by defined small molecules.
An-Dong ZhaoHua QinMeng-Li SunKui MaXiao-Bing FuPublished in: Military Medical Research (2020)
The results of the present study demonstrated the feasibility of chemically converting human and mouse astrocytes into motor neuron-like cells that are useful for neurodegenerative disease modeling and regenerative medicine.