Individual hippocampal subfield assessment indicates that matrix macromolecules and gliosis are key elements for the increased T2 relaxation time seen in temporal lobe epilepsy.
José Eduardo Peixoto-SantosLudmyla KandrataviciusTonicarlo Rodrigues VelascoJoao Alberto AssiratiCarlos Gilberto CarlottiRenata Caldo ScandiuzziCarlos Ernesto Garrido SalmonAntonio Carlos Dos SantosJoao Pereira LeitePublished in: Epilepsia (2016)
Our data indicate that astrogliosis, microgliosis, and CSPG expression correlate with the increased T2 relaxation time seen in the hippocampi of patients with TLE.