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Relationship Between Adalimumab Concentrations, Antidrug Antibodies, and Disease Activity in Rheumatoid Arthritis: A Cross-Sectional Observational Study.

Lisa K StampPaula E KeatingChristopher M A FramptonMurray L BarclayNiamh C FanningMelanie J MillierPaul A HessianJohn L O'Donnell
Published in: The Journal of rheumatology (2024)
ADA concentration correlates negatively with markers of inflammatory disease activity in RA, including IL-6. ADA concentration in the range 5 to 7 mg/L over the dose interval are associated with better disease control.
Keyphrases
  • disease activity
  • rheumatoid arthritis
  • juvenile idiopathic arthritis
  • rheumatoid arthritis patients
  • ankylosing spondylitis
  • systemic lupus erythematosus
  • interstitial lung disease
  • oxidative stress